New Study on the Gut-Brain Axis (Im Back?)

by Paleo Rob on 18/04/2016

So there is a new study about Gut Bacteria. I still think gut-bacteria is the next frontier of medicine, and the more studies that come out like this one, make me believe it even more. The Guardian has the right up.

Interesting throughout, but some key parts, emphasis mine.

Far from being silent partners that merely help to digest food, the bacteria in your gut may also be exerting subtle influences on your thoughts, moods, and behaviour

Last year, they published evidence that germ-free mice, which are completely devoid of gut bacteria, exhibit altered gene expression in the amygdala, a small, almond-shaped brain structure that is critical regulating emotions and social behaviour. The animals were reared in highly sterile conditions, so that bacteria cannot colonise their guts after birth – as a result certain genes involved in neuronal function appear to more active in their brains compared to those of normal mice.

The process of myelination, by which myelin is formed and laid down around axons, is crucial for development and maturation of the brain. During adolescence, the brain undergoes a protracted period of heightened neural plasticity, during which large numbers of synapses are eliminated in the prefrontal cortex, and a wave of myelination sweeps across this part of the brain. These processes refine the circuitry in the prefrontal cortex, and increase its connectivity to other brain regions. The increased plasticity make adolescents more susceptible to risky behaviour and mental health conditions such as schizophrenia, however.

The results have wider implications, though. There is growing evidence that the distribution of myelin in the brain can be modified in response to experience, and Cryan points to a 2012 study showing that social isolation impairs myelination in the prefrontal cortex of adult mice. The new findings therefore offer tantalizing clues about how gut bacteria might regulate brain plasticity in response to isolation and other social factors or environmental stimuli.

The last sentence is truly thought-provoking, and really show-cases the synchronous pathway of the axis. 

So eat your sauerkraut and kimchi, and have some yoghurt and kefir people! 

We still don’t know how good it is for you, but we know that it is…



Ahh the Olympics, were capitalism, politics and nationalism unite… oh also there is some sports apparently. But seriously, this was an interesting article...

“Veggie” diet blamed for poor performance of China’s women volleyball team

Fearing tainted meat, China’s women’s volleyball team has stuck to a strict vegetarian diet for the last three weeks, which the team’s coach is now blaming for his athletes’ abysmal performance.

  “They have showed significant decline in their strength and fitness” coach Yu Juemin said of his squad after Sunday’s defeat to the US.


I know this doesn’t really prove anything in the grand scheme of things, but still, its quite interesting!



Australia’s Obese Future

July 1, 2012

Here is a cool graphic from the Australian Science Media Centre. Don’t know too much about the organisation, but the infographic is quite informative.   Australian Science Media Centre The sad part is that throughout the period shown on the graphic, we have been pushed the low-fat, high seed oil mantra, and its obviously not working. […]

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Around the Health Web

June 30, 2012

New Study: Is a Calorie a Calorie? via Whole Health Source A new study in JAMA led by Dr. Cara B. Ebbeling and colleagues purports to challenge the idea that all calories are equally fattening (1).  Let’s have a look. Dietary Fiber Alters Gut Bacteria, Supports Gastrointestinal Health via ScienceDaily  A University of Illinois study […]

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Vegetables – Just add fat!

June 29, 2012

I like vegetables. I don’t hold them to the great esteem that most others hold them to, but I like them. To me they add a mix of flavour, texture and colour to a meal, and of course, they have some pretty decent nutritional properties. Your vegetables are a good source of vitamins and minerals, […]

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The Leangains FAQ

June 27, 2012

I am a huge fan of the Leangains program by Martin Berkhan. I really think it is one of the simplest yet most effective plans for gaining serious muscle mass, whilst lowering body fat. It is a perfect synergy of intermittent fasting, heavy lifting and good diet. Best of all, its very managable, and can […]

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From around the health web…

June 23, 2012

Low-carbohydrate diet proven to be very effective in type 1 diabetics (just as you’d expect) via Dr Briffas Blog A fundamental problem with diabetes is the usually-elevated levels of blood sugar (glucose) that go with it. These glucose molecules can react with proteins in the body, damaging them. This process – known as ‘glycation’ – […]

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Doc’s that go QUACK in the night.

April 10, 2012

As most office workers understand, there is no limit to the ridiculous health claims that are throne about around the coffee machine. Second maybe only to your local bro-gym (but a pretty dam close second), I have concluded there is no limit as to what people will do as a shortcut to get healthier (except […]

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N=1 Experiment Shows Butter as Effective as a Statin!

April 7, 2012

I got a kick out of this one; Greg here started eating a whole bunch of butter. Did his LDL cholesterol sky rocket? Nope. Actually his LDL levels dropped and HDL increased. This is a N=1 experiment, but interesting to say the least.     Don’t show your doctor.   Bookmark It Hide Sites

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Thing’s I’m Reading…

March 3, 2012

Cocoa May Enhance Skeletal Muscle Function A small clinical trial led by researchers at UC San Diego School of Medicine and VA San Diego Healthcare System (VASDHS) found that patients with advanced heart failure and type 2 diabetes showed improved mitochondrial structure after three months of treatment with epicatechin-enriched cocoa. Epicatechin is a flavonoid found […]

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